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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TP1730 | β-catenin peptide | ||
β-catenin peptide,(βCATp) is a naturally occurring self-peptide presented by Kb that very efficiently mediates positive selection of the OT-I thymocytes. | |||
TP1730L | β-catenin peptide acetate(265669-37-2 free base) | Others | |
β-catenin peptide(βCATp) acetate is a naturally occurring self-peptide presented by Kb that very efficiently mediates positive selection of the OT-I thymocytes. | |||
T6203 | Saxagliptin | BMS-477118,Onglyza | Proteasome , DPP-4 |
Saxagliptin (BMS-477118) is a selective and reversible DPP4 inhibitor with IC50 of 26 nM. | |||
T0178 | Saxagliptin hydrate | Onglyza hydrate,BMS-477118 hydrate | Proteasome , DPP-4 |
Saxagliptin hydrate (Onglyza hydrate) is a selective and reversible DPP4 inhibitor (IC50: 26 nM; Ki: 1.3 nM). | |||
TP1263 | Fz7-21 | (Ac)-LPSDDLEFWCHVMY-NH2 | Wnt/beta-catenin |
Fz7-21 ((Ac)-LPSDDLEFWCHVMY-NH2) is a peptide antagonist of FZD7 . It antagonises WNT3A-induced Wnt-β-catenin signalling in HEK293 expressing FZD7. Fz7-21 impairs Wnt/β-catenin signaling in HEK293 cells stimulated with e... | |||
TP1565L1 | Foxy-5 Ammonium Salt | Foxy-5 Ammonium Salt(881188-51-8 Free base) | Wnt/beta-catenin |
Foxy-5 Ammonium Salt is a WNT5A agonist, a mimetic peptide of WNT5A, a non-classical member of the Wnt family.Foxy-5 Ammonium Salt triggers cytoplasmic free calcium signaling without affecting β-catenin activation and in... | |||
T36275 | XStAx-VHLL | ||
Selective peptide-based β-catenin Degrader. Comprises a β-catenin-targeted stapled peptide, xStAx, linked to a VHL-binding peptide. Reduces β-catenin levels in HEK293T cells and colorectal cancer cell lines. Selectively ... | |||
T80124 | C-Peptide 1 (rat) | GSK-3 | |
C-Peptide 1 (rat), a β-catenin/GSK-3β activator and regulator of the Wnt/β-catenin signaling pathway, is utilized in cancer research [1]. | |||
T35550 | FRATide | ||
FRATtide inhibits the phosphorylation of Axin and β-catenin, inhibits GSK-3 binding to Axin, and is a peptide derived from the GSK-3 binding protein. | |||
TP1979 | NLS-StAx-h | ||
Wnt inhibitor (IC50 = 1.4 μM). Stapled peptide inhibitor of oncogenic Wnt signaling. Inhibits β-catenin-transcription factor interactions. Inhibits proliferation and migration of colorectal cancer cells. Cell permeable. | |||
T76060 | NLS-StAx-h TFA | ||
NLS-StAx-h TFA is a selective and cell-permeable stapled peptide that inhibits Wnt signaling, demonstrating an IC50 value of 1.4 μM and effectively suppressing β-catenin-transcription factor interactions. This compound e... | |||
TP1296 | Foxy-5 TFA(881188-51-8 free base) | Foxy-5 (TFA) | |
Foxy-5 is a peptide that mimics the WNT5A protein and is expected to reduce the mobility of the cancer cells. Foxy-5 triggers cytosolic free calcium signaling without affecting β-catenin activation and it impairs the mig... | |||
T75941 | Foxy-5 TFA | ||
Foxy-5 TFA, a WNT5A agonist and mimicking peptide of WNT5A (a non-canonical Wnt family member), induces cytosolic free calcium signaling without altering β-catenin activation. This compound inhibits the migration and inv... | |||
T75956 | Fz7-21 TFA | ||
Fz7-21 (Ac-LPSDDLEFWCHVMY-NH2) TFA, a potent peptide antagonist, selectively targets and binds to the FZD7 CRD subclass, significantly altering its CRD conformation and the structure of its lipid-binding groove. This com... |